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Merck's Plan to Win
The year 2005 brought significant change to Merck. Dick Clark, the head of the Merck Manufacturing Division, was named Merck's new chief executive officer and president. Promising new medicines and vaccines made important progress through our pipeline. And Merck's management team developed and began executing a strategy designed to return Merck to a leadership position in the pharmaceutical industry. The result of this effort, Merck's Plan to Win, was unveiled on December 15. Every part of the Company is already hard at work executing it.
Arcoxia®
(etoricoxib)
  • Osteoarthritis
  • Rheumatoid arthritis (adult)
  • Acute pain
  • Chronic low back pain
  • Dysmenorrhea (menstrual pain)
  • Acute gouty arthritis
Cancidas®
(caspofungin acetate)
  • Empiric therapy for presumed fungal infections for febrile, neutropenic patients
  • Treatment of invasive aspergillosis in patients who did not respond to or were intolerant of other antifungal therapies
  • Candida infections: intra-abdominal abscesses, peritonitis (infections within the lining of the abdominal cavity), pleural space infections (infections within the lining of the lung)
  • Candidemia (bloodstream infection)
  • Esophageal candidiasis
Comvax®
[Haemophilus b conjugate (meningococcal protein conjugate) and hepatitis B (recombinant) vaccine]
  • Simultaneous vaccination against Haemophilus influenzae type b disease and hepatitis B disease
Cosopt®
(dorzolamide hydrochloride and timolol maleate)
  • Lower intraocular pressure
Cozaar®
(losartan potassium)
  • High blood pressure
  • Reduction in progression of renal disease in patients with type 2 diabetes, hypertension and nephropathy
  • Reduction of stroke risk in patients with hypertension and left ventricular hypertrophy(1)
Crixivan®
(indinavir sulfate)
  • Treatment of HIV infection in combination with antiretroviral agents
Emend®
(aprepitant)
  • Prevention of nausea and vomiting induced by highly emetogenic chemotherapy
  • Prevention of nausea and vomiting induced by moderately emetogenic chemotherapy
Fosamax®
(alendronate sodium)
  • Treatment and prevention of postmenopausal osteoporosis
  • Reduction of osteoporotic fracture risk in postmenopausal women
  • Treatment of male osteoporosis to increase bone mass
  • Treatment of glucocorticoid-induced osteoporosis
  • Paget's disease of the bone
Fosamax Plus D™
(alendronate sodium/cholecalciferol)
  • Treatment of osteoporosis in postmenopausal women
  • Treatment to increase bone mass in men with osteoporosis
Hyzaar®
(losartan potassium and hydrochlorothiazide)
  • High blood pressure
  • Reduction of stroke risk in patients with hypertension and left ventricular hypertrophy(1)
Invanz®
(ertapenem sodium)
  • Treatment of moderate to severe infections caused by susceptible strains of aerobic and anaerobic bacteria, such as complicated intra-abdominal and complicated skin and skin structure infections
  • Treatment of moderate to severe complicated foot infection due to indicated pathogens in diabetic patients without osteomyelitis
Maxalt®
(rizatriptan benzoate)
  • Acute migraine
M-M-R® II
[measles, mumps and rubella virus vaccine live]
  • Simultaneous vaccination against measles, mumps, rubella
Pneumovax® 23
[pneumococcal vaccine polyvalent]
  • Vaccination against pneumococcal disease
Primaxin®
(imipenem and cilastatin)
  • Antibiotic
Propecia®
(finasteride)
  • Treatment of male pattern hair loss
ProQuad®
[measles, mumps, rubella and varicella (Oka/Merck) virus vaccine live]
  • Simultaneous vaccination against measles, mumps, rubella (German measles) and varicella (chickenpox) in children 12 months to 12 years of age
Proscar®
(finasteride)
  • Treatment of symptomatic benign prostate enlargement
Recombivax HB®
[hepatitis B vaccine (recombinant)]
  • Vaccination against hepatitis B
RotaTeq®
(rotavirus vaccine, live, oral pentavalent)
  • Vaccination against rotavirus gastroenteritis in infants
Singulair®
(montelukast sodium)
  • Chronic asthma — adults and children as young as
    12 months old
  • Seasonal allergic rhinitis — adults and children as
    young as age 2
  • Perennial allergic rhinitis (indoor/year-round allergies) — in adults and children 6 months of age and older
Stocrin®
(efavirenz)(2)
  • HIV infection
Timoptic-XE®
(timolol maleate ophthalmic gel forming solution)
  • Lower intraocular pressure
Trusopt®
(dorzolamide hydrochloride)
  • Lower intraocular pressure
Vaqta®
[hepatitis A vaccine inactivated]
  • Vaccination against hepatitis A
Varivax®
[varicella virus vaccine live (Oka/Merck)]
  • Vaccination against chickenpox
Vytorin®
(ezetimibe simvastatin)(3)
  • Elevated total cholesterol levels
  • Lower LDL cholesterol
  • Raise HDL cholesterol
  • Reduce triglycerides
Zetia®
(ezetimibe)(3)
  • Elevated cholesterol levels
Zocor®
(simvastatin)
  • Elevated total cholesterol levels
  • Associated total/coronary mortality(4)
  • Lower LDL cholesterol
  • Raise HDL cholesterol
  • Reduce triglycerides
  • Reduce stroke risk(4)
(1) There is evidence that this benefit does not apply to black patients.
(2) Efavirenz is marketed by Bristol-Myers Squibb as Sustiva in the U.S., Canada and certain European countries, and by Merck in the rest of the world as Stocrin.
(3) Vytorin (marketed as Inegy outside the U.S.) and Zetia (marketed as Ezetrol outside the U.S.) are marketed through a partnership with Schering-Plough Corporation.
(4) In patients with coronary heart disease or diabetes.
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