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Merck’s research pipeline continues to grow as we accelerate our discovery efforts. In the past year, we have advanced 26 candidates to the next clinical development stage. We currently have seven candidates in Phase III development, 17 distinct candidates in Phase II and another 23 in Phase I.

A Robust Pipeline

Updated February 15, 2008

Small molecules and biologics are given MK-number designations and vaccine candidates are given V-number designations.

  • Recent Advance Advanced Since February 2007
  • † Clinical program conducted by Allergan, Inc.
  • * Proof-of-Concept Molecule
  1. Phase I (1)

    1. Alzheimer's Disease, V950
    2. Atherosclerosis, MK-1903
    3. Atherosclerosis, MK-6213
    4. Cancer, MK-0646
    5. Cancer, MK-0752
    6. Cancer, MK-2461
    7. Cancer, MK-4721
    8. Cancer, V930
    9. Cardiovascular, MK-0448
    10. Cardiovascular, MK-1809
    11. Diabetes, MK-0941
    12. Diabetes, MK-2662
    13. Diabetes, MK-8245
    14. Infectious Disease, MK-3281
    15. Infectious Disease, MK-4965
    16. Infectious Disease, MK-7009
    17. Infectious Disease, MK-8122
    18. Infectious Disease, V512
    19. Neurologic, MK-4305
    20. Neurologic, MK-8998
    21. Ophthalmic, MK-0140
    22. Parkinson’s Disease, MK-0657
    23. Psychiatric Disease, MK-5757
  2. Phase II (1)

    1. Alzheimer’s Disease, MK-0249
    2. Atherosclerosis, MK-0859
    3. Atherosclerosis, MK-0633
    4. Cancer, MK-0457
    5. Cancer, MK-0822
    6. Cardiovascular, MK-8141
    7. Diabetes, MK-0893
    8. HPV, V502
    9. Infectious Disease, V419
    10. Infectious Disease, V710
    11. Neurologic, MK-0249
    12. Ophthalmic, SIRNA-027
    13. Pain, MK-2295 *
    14. Psychiatric Disease, MK-0249
    15. Respiratory Disease, MK-0633
    16. Sarcopenia, MK-2866
    17. Stroke, MK-0724

(1) Candidates shown in Phase I and Phase II include the most advanced candidate for a specific mechanism within a given therapeutic area. Back-up candidates, regardless of their phase of development; additional indications in the same therapeutic area; and additional claims, line extensions or formulations for in-line products are not shown.

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