OUR AREAS OF INTEREST

Biologics

Areas of Interest:

  • Novel biologics with either human genetics validation or clinical POC for the pathway
  • Immunomodulatory mechanisms (mAbs, etc)
  • Novel devices for SQ and IV delivery

Technologies of Interest:

  • Broadly applicable platform technologies to make biobetters
  • Half-life extension technologies for peptides and smaller biologics
  • Innovative therapeutic glycoproteins where the oligosaccharide moiety modulates the biochemical and physiological properties of the glycoproteins.
    Examples include:
    • Modulating potency via receptor-ligand interaction
    • Tissue-targeting (eg, through lectin interactions)
    • Improving protein solubility and / or stability
  • Technologies that enhance expression, production, formulation, stability, and bioavailability (via SQ administration) of proteins
  • Platforms for the generation and modification of engineered proteins displaying pharmaceutical properties
  • High-throughput antibody screening
    • especially functional screens suitable for accessing bi- or multi-specific therapeutics

Not Interested in:

  • Transgenic animal-based or plant-based antibody discovery or production systems for therapeutics
  • Basic phage display systems / libraries
  • Bi-specific platforms – but will still look at specific drugs

Areas of Interest

Click on the icons below for more information about your areas of interest.

Research & Enabling Technologies Atherosclerosis and Cardiovascular Diseases Biologics Respiratory and Immunology Diabetes and Endocrinology Infectious Diseases Neurosciences and Ophthalmology Oncology Therapeutics Vaccines Global Out-Licensing

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