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Pronunciations chlorpheniramine corticosteroid diphenhydramine hydrocortisone

For allergies affecting the nose and respiratory tract (such as hay fever), OTC antihistamines that can be taken by mouth are available (see Allergic Reactions: Antihistamines). Examples are chlorpheniramine Some Trade Names
CHLOR-TRIMETON
TELDRIN
and diphenhydramine Some Trade Names
BENADRYL
NYTOL
SOMINEX
. Taking an antihistamine to treat allergies requires the same precautions as taking a cold remedy containing an antihistamine (see Over-the-Counter (OTC) Drugs: Antihistamines). (Several new antihistamines that have fewer side effects are available, but most require a prescription.)

For allergies affecting the skin (such as poison ivy), creams or lotions that contain an antihistamine, such as diphenhydramine Some Trade Names
BENADRYL
NYTOL
SOMINEX
, can be applied to the skin (see Diagnosis and Treatment of Skin Disorders: Topical Preparations). Lotions, creams, and ointments that contain hydrocortisone Some Trade Names
See Cortisol
, a corticosteroid, are effective in relieving itching associated with allergies, minor skin irritations, and inflammation. Long-term use of corticosteroid products can cause side effects, such as irreversible thinning and redness of the skin, but the risk with hydrocortisone Some Trade Names
See Cortisol
is minimal.

Last full review/revision February 2003