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THE MERCK MANUAL MEDICAL LIBRARY: The Merck Manual of Medical Information--Home Edition
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Chromium Picolinate

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Background: Chromium is a mineral required in small quantities by the body. It enables insulinSome Trade Names
HUMULIN
NOVOLIN
to function normally and helps the body process (metabolize) carbohydrates and fats. Good sources of chromium include carrots, potatoes, broccoli, whole-grain products, and molasses. Picolinate, a by-product of the amino acid tryptophan, is paired with chromium in supplements because it is claimed to help the body absorb chromium more efficiently.

Medicinal Claims: As a dietary supplement, chromium picolinate is used to promote weight loss, build muscle, reduce body fat, and enhance the function of insulinSome Trade Names
HUMULIN
NOVOLIN
, but these effects have not been proved. It may lower levels of cholesterol and triglycerides.

Possible Side Effects: Some evidence suggests that chromium picolinate damages chromosomes and consequently may cause cancer.

Last full review/revision February 2003

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