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THE MERCK MANUAL MEDICAL LIBRARY: The Merck Manual of Medical Information--Home Edition
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Dehydroepiandrosterone (DHEA)

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Background: Dehydroepiandrosterone (DHEA) is a steroid produced in the adrenal glands and converted into sex hormones (estrogensSome Trade Names
PREMARIN
and androgens). DHEA's effects on the body are similar to those of testosteroneSome Trade Names
DELATESTRYL
DEPOTESTOSTERONE
. DHEA can be extracted from the Mexican yam.

Medicinal Claims: DHEA supplements may stimulate the immune system. They are used to improve mood, energy, sense of well-being, and the ability to function well under stress. Other uses include deepening nightly sleep, lowering cholesterol levels, and decreasing body fat. Many athletes claim that DHEA builds muscles. It is also claimed to reverse aging and improve brain function in people with Alzheimer's disease. The medicinal claims of DHEA have not been proved.

Possible Side Effects: Theoretically, DHEA may result in breast enlargement in men and hairiness in women and may stimulate the growth of certain prostate and breast cancers, but these effects have not been substantiated. DHEA should not be used by children attempting to build muscle or enhance athletic performance.

Last full review/revision February 2003

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