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Pronunciations anorexia nervosa esophagus parotid gland serotonin

Bulimia nervosa is characterized by the repeated rapid consumption of large amounts of food (bingeing), followed by attempts to rid the body of the excess food consumed (purging).

• People eat large amounts of food, then induce vomiting, use laxatives, diet, or vigorously exercise to compensate.
• Doctors suspect the diagnosis when people are overly concerned about their weight and their weight fluctuates a lot.
• Cognitive-behavioral therapy, a selective serotonin reuptake inhibitor (a type of antidepressant), or both may be used to treat the disorder.

As in anorexia nervosa, bulimia nervosa is influenced by hereditary and social factors. Also as in anorexia nervosa, most people who have bulimia nervosa are young women, are deeply concerned about body shape and weight, and belong to the middle or upper socioeconomic classes. Bulimia nervosa affects mainly adolescents and young adults, occurring in 1.6% of females and 0.5% of males.

Symptoms

People repeatedly eat in binges. That is, they eat large amounts of food within a relatively short period of time, often within 2 hours. Emotional stress often triggers the binge-purge cycle, which usually is done in secret. Bingeing, which is accompanied by a feeling of a loss of control, usually includes eating when not hungry and eating to the point of pain. People tend to consume high-calorie foods, such as ice cream and cake. The amount of food consumed varies and sometimes involves thousands of calories. Binges may occur as often as several times a day.

Did You Know? People with bulimia tend to feel very remorseful or guilty about their behavior. People with bulimia may have scars on their knuckles from using their fingers to induce vomiting.

In an attempt to counteract the effects of the excess food, people use various means to purge:

• Vomiting
• Taking laxatives
• Rigorously dieting or fasting
• Overexercising
• Any combination of the above

Many also take diuretics to treat perceived bloating. However, unlike in anorexia nervosa, the body weight of people with bulimia nervosa tends to fluctuate around normal.

Self-induced vomiting can erode tooth enamel, enlarge the salivary glands in the cheeks (parotid glands), and inflame the esophagus. Vomiting and purging can lower potassium levels in the blood, causing abnormal heart rhythms. Sudden death can result from an abnormal heart rhythm in people who repeatedly take large quantities of ipecac to induce vomiting. Rarely, people who have this disorder eat so much during a binge that their stomach ruptures or their esophagus tears, leading to life-threatening complications.

Compared with people who have anorexia nervosa, those who have bulimia nervosa tend to be more aware of their behavior and to feel remorseful or guilty about it. They are more likely to admit their concerns to a doctor or other confidant. Generally, people with bulimia nervosa are more outgoing. They also are more prone to impulsive behavior, drug or alcohol abuse, and depression.

Diagnosis

Bulimia nervosa is suspected when people, particularly young women, express marked concern about weight gain and have wide fluctuations in weight, especially if there is evidence of excessive laxative use (such as diarrhea and abdominal cramps). Doctors also check for other clues:

• Swollen salivary glands in the cheeks
• Scars on the knuckles from using the fingers to induce vomiting
• Erosion of tooth enamel from stomach acid
• A low level of potassium detected by a blood test

Technically, the diagnosis is confirmed when people describe binge-purge behavior and report having two or more binge-eating episodes a week for at least 3 months. But doctors may diagnose the disorder without this information when symptoms strongly suggest it.

Treatment

The two most effective approaches to treatment are cognitive-behavioral therapy and drug therapy. Treatment may be most effective when both are used.

In cognitive-behavioral therapy, dysfunctional thoughts are identified and examined, and people are helped to give them up. People meet with a therapist once or twice a week over a period of 4 to 5 months, for a total of about 16 to 20 sessions. Cognitive-behavioral therapy reduces the frequency of bingeing in about two thirds of people with bulimia and stops bingeing altogether in about one third. People who have had this therapy continue to reduce or refrain from bingeing for at least 1 year.

Selective serotonin reuptake inhibitors, a type of antidepressant, are somewhat effective and best used with cognitive-behavioral therapy in the treatment of bulimia nervosa. However, when the drugs are stopped, bingeing frequently recurs.

Last full review/revision June 2008 by Albert J. Stunkard, MD