Merck Manual

Please confirm that you are not located inside the Russian Federation

honeypot link

Overview of Hereditary Periodic Fever Syndromes

By

Gil Amarilyo

, MD, Tel Aviv University

Reviewed/Revised Dec 2023
VIEW PROFESSIONAL VERSION
Topic Resources

Hereditary periodic fever syndromes are hereditary disorders that periodically cause episodes of fever and other symptoms that are not due to usual childhood infections or any other obvious disorder.

The most common hereditary periodic fever syndrome across all age groups is

A similar disorder that causes episodes of fever but is not thought to be hereditary is

Other less common syndromes include the following:

Symptoms of hereditary periodic fever syndromes usually begin during childhood. Fewer than 10% of people develop symptoms after age 18. People periodically have attacks of fever and inflammation but feel well between attacks.

Drugs Mentioned In This Article

Generic Name Select Brand Names
Kineret
Arcalyst
Ilaris
Deltasone, Predone, RAYOS, Sterapred, Sterapred DS
Enbrel
ABRILADA, AMJEVITA , CYLTEZO, HADLIMA, Hulio, Hulio PEN, Humira, HUMIRA PEN, Hyrimoz, Idacio, YUFLYMA, YUSIMRY
AVSOLA, INFLECTRA, Remicade, RENFLEXIS, Zymfentra
Emtet-500, Panmycin, Sumycin
Absorica, Absorica LD, Accutane, Amnesteem , Claravis , MYORISAN, Sotret, ZENATANE
NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
VIEW PROFESSIONAL VERSION
quiz link

Test your knowledge

Take a Quiz!
iOS ANDROID
iOS ANDROID
iOS ANDROID
TOP