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Echocardiography uses ultrasound waves to produce an image of the heart and great vessels. It helps assess heart wall thickness (eg, in hypertrophy or atrophy) and motion and provides information about ischemia and infarction. It can be used to assess diastolic filling patterns of the left ventricle, which can help in the diagnosis of left ventricular hypertrophy, hypertrophic or restrictive cardiomyopathy, severe heart failure, constrictive pericarditis, and severe aortic regurgitation.
In transthoracic echocardiography (TTE), a transducer is placed along the left or right sternal border, at the cardiac apex, at the suprasternal notch (to visualize the aortic valve, left ventricular outflow tract, and descending aorta), or over the subcostal region. In transesophageal echocardiography (TEE), a transducer on the tip of an endoscope visualizes the heart via the esophagus.
TTE, the most common technique, provides 2-dimensional tomographic images of most major cardiac structures. TEE is used to assess posterior cardiac structures (eg, left atrium, left atrial appendage, interatrial septum) because they are closer to the esophagus than to the anterior chest wall. TEE can also produce images of the ascending aorta, which arises behind the 3rd costal cartilage; of structures < 3 mm (eg, thrombi, vegetations); and of prosthetic valves.
Two-dimensional (cross-sectional) echocardiography is most commonly used; contrast and spectral Doppler echocardiography provide additional information.
Contrast echocardiography is 2-dimensional TTE done while agitated saline is rapidly injected into the cardiac circulation. Agitated saline develops microbubbles, which produce a cloud of echoes in the right cardiac chambers and which, if a septal defect is present, appear on the left side of the heart. Usually, the microbubbles do not traverse the pulmonary capillary bed; however, one agent, sonicated albumin microbubbles, can do so and can enter left heart structures after IV injection.
Spectral Doppler echocardiography can record velocity, direction, and type of blood flow. This technique is useful for detecting abnormal blood flow (eg, due to regurgitant lesions) or velocity (eg, due to stenotic lesions). Spectral Doppler echocardiography does not provide spatial information about the size or shape of the heart or its structures.
Color Doppler echocardiography combines 2-dimensional and spectral Doppler echocardiography to provide information about the size and shape of the heart and its structures as well as the velocity of and direction of blood flow around the valves and outflow tracts. Color is used to code blood flow information; by convention, red is toward and blue away from the transducer.
Stress echocardiography is TTE done during and after exercise or pharmacologic stress. Stress echocardiography shows regional wall motion abnormalities that result from an imbalance in blood flow in epicardial blood vessels during stress. Computer programs can provide side-by-side assessment of ventricular contraction during systole and diastole at rest and under stress. Exercise and pharmacologic protocols are the same as those used in radionuclide stress testing. Stress echocardiography and radionuclide stress testing detect ischemia about equally well. The choice between tests is often based on availability, the provider's experience, and cost.
Last full review/revision November 2005
Content last modified November 2005
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