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Acute otitis
media is a bacterial or viral infection of the middle ear, usually
accompanying a URI. Symptoms include otalgia, often with systemic symptoms
(eg, fever, nausea, vomiting, diarrhea), especially in the very
young. Diagnosis is based on otoscopy. Treatment is with analgesics
and sometimes antibiotics.
Although acute otitis media (AOM) can occur at any age, it is most common between ages 3 mo and 3 yr. At this age, the eustachian tube is structurally and functionally immature; the angle of the eustachian tube is more horizontal; and the angle of the tensor veli palatini muscle and the cartilaginous eustachian tube renders the opening mechanism less efficient.
The etiology may be viral or bacterial. Viral infections are often complicated by secondary bacterial infection. In neonates, gram-negative enteric bacilli, particularly Escherichia coli, and Staphylococcus
aureus cause AOM. In older infants and children < 14 yr, the most common organisms are Streptococcus pneumoniae, Moraxella
(Branhamella) catarrhalis, and nontypeable Haemophilus
influenzae; less common causes are group A β-hemolytic streptococci and S. aureus. In patients > 14 yr, S. pneumoniae, group A β-hemolytic streptococci, and S. aureus are most common, followed by H. influenzae.
In rare cases, bacterial middle ear infection spreads locally, resulting in acute mastoiditis, petrositis, or labyrinthitis. Intracranial spread is extremely rare and usually causes meningitis, but brain abscess, subdural empyema, epidural abscess, lateral sinus thrombosis, or otitic hydrocephalus may occur. Even with antibiotic treatment, intracranial complications are slow to resolve, especially in immunocompromised patients.
Symptoms and Signs
The usual initial symptom is earache, often with hearing loss. Infants may simply be cranky or have difficulty sleeping. Fever, nausea, vomiting, and diarrhea often occur in young children. Otoscopic examination can show a bulging, erythematous tympanic membrane (TM) with indistinct landmarks and displacement of the light reflex. Air insufflation (pneumatic otoscopy) shows poor mobility of the TM. Spontaneous perforation of the TM causes serosanguineous or purulent otorrhea.
Severe headache, confusion, or focal neurologic signs may occur with intracranial spread of infection. Facial paralysis or vertigo suggests local extension to the fallopian canal or labyrinth.
Diagnosis
Diagnosis usually is clinical. Except for fluid obtained during myringotomy, cultures are not generally obtained.
Treatment
Although 80% of cases resolve spontaneously, in the US, antibiotics are often given (see Table 2: Middle Ear and Tympanic Membrane Disorders: Guidelines for Using Antibiotics in Acute Otitis Media ). Antibiotics relieve symptoms quicker (although results after 1 to 2 wk are similar) and may reduce the chance of residual hearing loss and labyrinthine or intracranial sequelae. However, with the recent emergence of resistant organisms, pediatric organizations have strongly recommended initial antibiotics only for those at highest risk (eg, those who are younger or more severely ill—see Table 2: Middle Ear and Tympanic Membrane Disorders: Guidelines for Using Antibiotics in Acute Otitis Media) or for those with recurrent AOM (eg, ≥ 4 episodes in 6 mo). Others, provided there is good follow-up, can safely be observed for up to 72 h and given antibiotics only if no improvement is seen; if follow-up by phone is planned, a prescription can be given at the initial visit to save time and expense.
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Table 2
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Guidelines for Using Antibiotics
in Acute Otitis Media
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Age
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Diagnosis Certain
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Diagnosis Uncertain
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< 6 mo
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Antibiotics
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Antibiotics
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6 mo to 2 yr
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Antibiotics
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Antibiotics if illness severe*
Observe 72 h if illness not severe†
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≥ 2 yr
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Antibiotics if illness severe
Observe 72 h if illness not severe
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Observe 72 h
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*Temperature ≥ 39.5°C rectally any time within previous 24 h; moderate to severe otalgia; or physician's judgment that child is seriously ill.
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†Appropriate only if phone or office follow-up assured within 72 h. Antibiotics are started if no improvement.
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Modified from Rosenfeld RM: Observation option toolkit for acute otitis media. Int J Pediatr Otorhinolaryngol 58:1–8, 2001.
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All patients receive analgesics (eg, acetaminophen , ibuprofen ). In adults, topical intranasal vasoconstrictors, such as phenylephrine 0.25% 3 drops q 3 h, improve eustachian tube function. To avoid rebound congestion, these preparations should not be used > 4 days. Systemic decongestants (eg, pseudoephedrine 30 to 60 mg po q 6 h prn) may be helpful. Antihistamines (eg, chlorpheniramine 4 mg po q 4 to 6 h for 7 to 10 days) may improve eustachian tube function in people with allergies but should be reserved for the truly allergic. For children, neither vasoconstrictors nor antihistamines are of benefit.
Myringotomy may be done for a bulging TM, particularly if severe or persistent pain, fever, vomiting, or diarrhea is present. The patient's hearing, tympanometry, and TM appearance and movement are monitored until normal.
Prevention
Routine childhood vaccination against pneumococci (with pneumococcal conjugate vaccine), H.
influenzae type B, and influenza decreases the incidence of AOM. Infants should not sleep with a bottle, and elimination of household smoking may decrease incidence.
Last full review/revision February 2008 by Richard T. Miyamoto, MD
Content last modified February 2008
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