Merck Manual

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Overview of Osteochondroses

By

Frank Pessler

, MD, PhD, Helmholtz Centre for Infection Research

Reviewed/Revised Nov 2022
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Osteochondroses are noninflammatory, noninfectious derangements of bony growth at various ossification centers. These derangements occur during the period of greatest developmental activity and affect the epiphyses.

Etiology of osteochondroses is typically unknown; some of the disorders have a familial component, but inheritance is complex. Osteochondroses differ in their anatomic distribution, course, and prognosis; they typically cause pain and have important orthopedic implications. Common examples include

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