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Temporomandibular Disorders (TMDs)

By

Gary D. Klasser

, DMD, Louisiana State University School of Dentistry

Reviewed/Revised Sep 2023
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The temporomandibular joints are the connections between the temporal bones of the skull and the lower jawbone (mandible). There are 2 temporomandibular joints, one on each side of the face just in front of the ears. Ligaments, tendons, and muscles support the joints and are responsible for jaw movement.

The temporomandibular joint (TMJ) is one of the most complicated joints in the body: It opens and closes like a hinge and slides forward, downward, backward, and from side to side. During chewing, it may sustain an enormous amount of pressure depending on the position and health of the upper and lower teeth, which act much like a doorstop for the joint during closing. The TMJ contains a piece of dense fibrous tissue called the articular disk. The disk serves as a cushion between the skull and the lower jawbone, keeping them from rubbing against each other.

TMDs, previously called TMJ disorders, are most common among women in their early 20s and those between the ages of 40 and 50. In rare cases, infants are born with TMJ abnormalities. TMDs include problems with the joints, the muscles, and the bands of fibrous tissue that connect them (fascia).

Causes of Temporomandibular Disorders

Most often, the cause of a temporomandibular disorder (TMD) is a combination of muscle tension and anatomic problems within the joints. Sometimes there is a psychologic component as well as other factors. Clenching and grinding of the teeth (bruxism Teeth Grinding Teeth grinding (bruxism) is clenching or grinding the teeth. Teeth grinding can occur during sleep (called sleep bruxism) and while awake (awake bruxism).Teeth grinding eventually wears down... read more ), bodywide disorders (such as osteopenia, autoimmune disorders, connective tissue disorders, or genetic bone disorders), infections, injury, misalignment Malocclusion Malocclusion is abnormal alignment of the teeth and the way in which the upper and lower teeth fit together. Normally, the upper teeth overlap slightly outside the lower teeth. This overlap... read more Malocclusion of teeth, and even constant gum chewing can cause symptoms. Specific causes include

  • Muscle fatigue and overuse, leading to temporomandibular myofascial pain syndrome

  • Internal temporomandibular joint (TMJ) derangement

  • Arthritis

  • Ankylosis

  • Hypermobility

Temporomandibular myofascial pain syndrome

Temporomandibular myofascial pain syndrome is the most common disorder affecting the temporomandibular region. Muscle pain and tightness around the jaw and limited mouth opening occur, as well as headache and pain in other areas of the head and neck. Pain is caused mainly by muscle fatigue or overuse, sometimes resulting from clenching or grinding the teeth Teeth Grinding Teeth grinding (bruxism) is clenching or grinding the teeth. Teeth grinding can occur during sleep (called sleep bruxism) and while awake (awake bruxism).Teeth grinding eventually wears down... read more while awake or asleep due to psychologic or sleep-related stress. Clenching and grinding while asleep exert far more force than clenching and grinding while awake. Pain can also be brought on by injury to the head or neck, sleep disorders Overview of Sleep Sleep is necessary for survival and good health, but why sleep is needed and exactly how it benefits people are not fully understood. One of sleep's benefits is its restorative effect on people's... read more , problems of misalignment of the upper and lower sets of teeth Malocclusion Malocclusion is abnormal alignment of the teeth and the way in which the upper and lower teeth fit together. Normally, the upper teeth overlap slightly outside the lower teeth. This overlap... read more Malocclusion , or even toothache Toothache Toothache, pain in and around the teeth, is a common problem, particularly among people with poor oral hygiene. Pain may be constant, felt after stimulation (from heat, cold, sweet food or drink... read more . The TMJ can be normal. Temporomandibular myofascial pain syndrome is more common among women and typically affects women in their early 20s and women who are nearing or going through menopause.

The Temporomandibular Joint

The Temporomandibular Joint

Internal temporomandibular joint derangement

In the most common form of internal TMJ derangement, the disk inside the joint lies in front of (anterior to) its normal position. The disk can be moved out of place when the ligaments that hold it in place become elongated or, often, stretched due to injury to the joint (sprained ligament).

Internal TMJ derangement can occur with or without reduction. Reduction means the parts of a joint have returned to their normal positions. Disk displacement with reduction is more common than displacement without reduction and occurs in about one third of the adult population. In derangement with reduction, the disk lies in front of its normal position only when the mouth is closed. As the mouth opens and the jaw slides forward, the disk slips back into its normal position, often making a popping or clicking sound. As the mouth closes, the disk slips forward again. In internal TMJ derangement without reduction, the disk never slips back into its normal position, and the degree to which the mouth can be opened is limited. TMJ derangement can cause inflammation around the joint (capsulitis). Internal TMJ derangements may or may not be painful.

Arthritis

Arthritis in a temporomandibular joint may result from osteoarthritis, rheumatoid arthritis, infectious arthritis, or injury, particularly injury that causes bleeding into the joint. Such injuries are fairly common among children who are struck directly on the chin or on the side of the chin.

Osteoarthritis Osteoarthritis (OA) Osteoarthritis is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, and loss of function. Arthritis due to damage of joint... read more Osteoarthritis (OA) , a type of arthritis in which the cartilage of the body's joints degenerates, is most common among people over age 50. Osteoarthritis of the TMJ may occur when the fibrocartilage disk inside the joint is displaced or has developed holes, causing the bone of the joint to change shape as part of degenerative changes.

Rheumatoid arthritis Rheumatoid Arthritis (RA) Rheumatoid arthritis is an inflammatory arthritis in which joints, usually including those of the hands and feet, are inflamed, resulting in swelling, pain, and often destruction of joints.... read more Rheumatoid Arthritis (RA) , a disease in which the body attacks its own cells (an autoimmune disease) causing inflammation, affects the temporomandibular joint in about 17% of people with this type of arthritis. The temporomandibular joint is usually among the last joints to be affected by rheumatoid arthritis.

Infectious arthritis Infectious Arthritis Infectious arthritis is infection in the fluid and tissues of a joint usually caused by bacteria but occasionally by viruses or fungi. Bacteria, viruses, or fungi may spread through the bloodstream... read more is caused by an infection that has spread from an adjoining area of the head or neck or that has been carried by the bloodstream to the joint from another part of the body.

Traumatic arthritis, which is arthritis caused by an injury (such as when the jaw is stretched widely during a difficult tooth extraction), is rare.

Ankylosis

Ankylosis is loss of joint movement resulting from a fibrosing (scarring) or fusion of bones within the joint or from calcification (the deposit of calcium into body tissues) of the ligaments around it. Ankylosis most often results from an injury or an infection, but it may be apparent at birth or a result of rheumatoid arthritis.

Hypermobility

Hypermobility (looseness of the jaw) results when the ligaments that hold the joint together become excessively elongated, like being double-jointed. In hypermobility, dislocation is usually caused by the shape of the joints, ligament looseness (laxity), and muscle tension. It may be caused by trying to open the mouth too wide or by being struck on the jaw.

Symptoms of Temporomandibular Disorders

Symptoms of temporomandibular disorders (TMDs) include headaches, tenderness of the chewing muscles, and clicking or popping or locking of the joints. Sometimes the pain seems to occur near the joint rather than in it. Temporomandibular disorders may be the reason for recurring headaches that do not respond to usual medical treatment. Other symptoms include pain or stiffness in the neck and shoulders, dizziness, earaches or stuffiness in the ears, and disrupted sleep.

People with temporomandibular disorders often have difficulty opening their mouth wide. For example, most people without temporomandibular disorders can place the tips of their index, middle, and ring fingers held together and placed horizontally in the space between the upper and lower front teeth without forcing. For people with temporomandibular disorders (with the exception of those with hypermobility), this space usually is markedly smaller.

Temporomandibular myofascial pain syndrome

People with temporomandibular myofascial pain syndrome (previously known as temporomandibular joint [TMJ] syndrome or TMJ dysfunction) may feel pain, fatigue, and tightness on the sides of the face when awakening or after stressful periods during the day. Clenching and grinding of the teeth Teeth Grinding Teeth grinding (bruxism) is clenching or grinding the teeth. Teeth grinding can occur during sleep (called sleep bruxism) and while awake (awake bruxism).Teeth grinding eventually wears down... read more while asleep and sleep-disordered breathing, such as obstructive sleep apnea Sleep Apnea Sleep apnea is a serious disorder in which breathing repeatedly stops long enough to disrupt sleep and often temporarily decrease the amount of oxygen and increase the amount of carbon dioxide... read more Sleep Apnea , may cause a person to awaken with a headache, which may slowly diminish over the day. However, some people have symptoms while awake, including a headache, if they continue to clench and grind their teeth while awake. As the jaw opens, it may move slightly (deviate) to one side or the other and may not open all the way. The chewing muscles are typically painful and tender to the touch. Small spots or knots in the muscles (called trigger points) are tender and when pressed can cause referred pain in other locations in the head and neck.

Internal temporomandibular joint derangement

Internal joint derangement related to anterior disk displacement with reduction usually causes a clicking or popping sound in the joint when the mouth opens wide or the jaw shifts from side to side. Other people are sometimes able to hear these sounds. In many people, these joint sounds are the only symptoms. However, some people also have pain, particularly when chewing foods with a tough consistency. In a small percentage of people, these sounds progress to locking of the joints.

Internal joint derangement related to anterior disk displacement without reduction does not cause a sound but makes it difficult for people to open their mouth wide. It usually causes pain and a feeling that the joint is out of place. Typically, this type of joint derangement starts suddenly in people whose joint previously clicked all the time (anterior disk displacement with reduction). Sometimes people discover they are not able to fully open their jaw when they wake up. After 6 to 12 months, the pain may decrease, and the limitation on how much the mouth can be opened may resolve.

Arthritis

With osteoarthritis Osteoarthritis (OA) Osteoarthritis is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, and loss of function. Arthritis due to damage of joint... read more Osteoarthritis (OA) , because it occurs mainly when the disk is out of place or has developed holes, the person feels and often hears a grating sensation in the temporomandibular joints when opening and closing the mouth. Stiffness, mild pain, or a combination may occur. When osteoarthritis is severe, the top of the jawbone flattens out, and the person cannot open the mouth wide. The jaw may also shift toward the affected side, and the person may be unable to move it back. The person may notice a change in how the upper and lower teeth meet on the unaffected side.

Rheumatoid arthritis Rheumatoid Arthritis (RA) Rheumatoid arthritis is an inflammatory arthritis in which joints, usually including those of the hands and feet, are inflamed, resulting in swelling, pain, and often destruction of joints.... read more Rheumatoid Arthritis (RA) causes pain, swelling in the temporomandibular joint, and limited jaw movement. It usually affects both temporomandibular joints about equally, which is rarely the case in other types of TMDs. When rheumatoid arthritis is severe, especially in children, the top of the jawbone may degenerate and shorten, causing deformities of the face. This damage can lead to rapid misalignment Malocclusion Malocclusion is abnormal alignment of the teeth and the way in which the upper and lower teeth fit together. Normally, the upper teeth overlap slightly outside the lower teeth. This overlap... read more Malocclusion of many or all of the upper and lower teeth. Though rare, if the damage is severe, the bones of the joint may eventually fuse together (ankylosis).

Traumatic arthritis causes pain and tenderness in the temporomandibular joint, and limitation of jaw movement.

Ankylosis

Typically, fusion of the ligaments and bone around the joint (extra-articular ankylosis) is not painful, but the mouth can open only about 1 inch (about 2½ centimeters) or less. Fusion of bones within the joint (intra-articular ankylosis) causes pain and more severely limits jaw movement.

Hypermobility

In a person with hypermobility, the jaw may slip forward completely out of its socket (dislocate), causing pain and an inability to close the mouth. Dislocation Jaw Dislocation A dislocated jaw (dislocated mandible) generally is a very painful, urgent dental problem that needs the prompt attention of a doctor or dentist. The mouth cannot be closed, and the jaw may... read more may occur suddenly and repeatedly.

Diagnosis of Temporomandibular Disorders

  • A dentist's or doctor's evaluation

  • Sometimes imaging tests

  • For infectious arthritis, aspiration of fluid

  • Sometimes polysomnography (sleep study)

A dentist or doctor almost always diagnoses a temporomandibular disorder based solely on a person's medical and dental history and on a physical examination. Part of the examination involves gently pressing on the side of the face or placing the little finger in the person's ear and gently pressing forward while the person opens and closes the jaw, and listening and feeling for sounds of catching, clicking, or popping. Also the doctor gently presses on the chewing muscles to detect pain or tenderness and notes whether the jaw slides when the person bites. The person is asked to open the mouth as wide as is comfortable. An average-sized person can open the mouth at least 1½ inches (about 4 centimeters).

When a doctor suspects an internal joint derangement, further tests can be done. Magnetic resonance imaging Magnetic Resonance Imaging (MRI) Magnetic resonance imaging (MRI) is a type of medical imaging that uses a strong magnetic field and very high frequency radio waves to produce highly detailed images. During an MRI, a computer... read more Magnetic Resonance Imaging (MRI) (MRI) is the standard with which doctors assess whether internal joint derangement has occurred or why a person is not responding to treatment.

Infectious arthritis may be suspected when the area over and around the temporomandibular joint is inflamed and when movement of the joint is painful and limited. Infection in another part of the body serves as a clue as well. To confirm the diagnosis of infectious arthritis, the doctor may insert a needle into the temporomandibular joint and withdraw fluid (aspiration), which is then analyzed for bacteria.

If hypermobility is the cause, the person typically can open the mouth wider than the breadth of 3 fingers. The jaw may be chronically dislocated. If ankylosis is the cause, the jaw's range of motion tends to be markedly reduced.

If symptoms of muscle pain and tightness continue, doctors may arrange testing for a sleep disorder. This test is called polysomnography Testing .

Treatment of Temporomandibular Disorders

  • Oral appliance therapy and pain relievers

  • Self-help measures

  • Sometimes physical therapy

  • Sometimes surgery

  • Sometimes other medications (such as muscle relaxants, sleep aids, or botulinum toxin)

Treatment varies considerably according to the cause. Two common treatments are oral appliance therapy (also called splint therapy or a mouth guard) and analgesics such as nonsteroidal anti-inflammatory drugs Nonsteroidal Anti-Inflammatory Drugs Pain relievers (analgesics) are the main drugs used to treat pain. Doctors choose a pain reliever based on the type and duration of pain and on the drug's likely benefits and risks. Most pain... read more (NSAIDs) to relieve pain.

Temporomandibular myofascial pain syndrome

Oral appliance

An oral appliance often is the main treatment for jaw muscle pain and tightness. For people who realize that they clench or grind their teeth, oral appliance therapy can help them break the habit. A thin plastic oral appliance is made by a dentist to fit over either the upper or the lower set of teeth and is adjusted to give the person an even bite. The oral appliance, usually worn while sleeping (a nightguard), often reduces grinding and clenching, allowing the jaw muscles to rest and recover. For pain while awake, an oral appliance allows the jaw muscles to remain relaxed and the bite to be stable, thereby reducing discomfort. The oral appliance can also prevent damage to teeth that are under exceptional stress from the grinding and clenching. Oral appliances are used while awake only until symptoms subside, usually less than 8 weeks. Longer use may be warranted depending on the severity of symptoms.

Self-help measures

People should use self-help measures to relieve pain and restore normal function.

Physical therapy

Physical therapy may also be prescribed. Physical therapy may involve ultrasound treatment, electromyographic biofeedback (in which the person learns to relax the muscles), spray and stretch exercises (in which the jaw is stretched open after the skin over the painful area has been sprayed with a skin refrigerant or numbed with ice). Transcutaneous electrical nerve stimulation (TENS—see sidebar Physical Therapy for Jaw Muscles Physical Therapy for Jaw Muscles Physical Therapy for Jaw Muscles ) also may help. Stress management, sometimes along with electromyographic biofeedback, and counseling help some people.

Physical Therapy for Jaw Muscles

  • Ultrasound is a method of delivering deep heat to painful areas. When warmed by the ultrasound, the blood vessels dilate, and the blood can more quickly carry away accumulated muscle waste products that may cause pain.

  • Electromyographic biofeedback monitors muscle activity with a gauge. The person attempts to relax the entire body or a specific muscle while watching the gauge. In this way, the person learns to control or relax particular muscles.

  • Spray-and-stretch exercises involve spraying a skin refrigerant or applying ice over the painful area, so the jaw muscles can be stretched open.

  • Transcutaneous electrical nerve stimulation Electrical stimulation (TENS) involves using a device that stimulates the nerve fibers that do not transmit pain. The resulting impulses are thought to block the painful impulses that the person has been feeling.

Medications

Medications may also be helpful. For instance, muscle-relaxers, such as cyclobenzaprine, may be prescribed to ease tightness and pain. A benzodiazepine (antianxiety medication that also relaxes muscles) can sometimes be taken temporarily at bedtime to help relieve symptoms. However, these medications are not a cure, generally are not recommended for older adults, and are prescribed for only a short time, usually for a month or less.

Analgesics such as acetaminophen or other NSAIDs also may help relieve pain. A prescription for opioid analgesics is usually not given because treatment may be needed for some time and these drugs can be addictive. Sleep aids (sedatives) may be used occasionally and for a short time to help people who have trouble sleeping because of the pain. People who may have a sleep disorder, such as obstructive sleep apnea Sleep Apnea Sleep apnea is a serious disorder in which breathing repeatedly stops long enough to disrupt sleep and often temporarily decrease the amount of oxygen and increase the amount of carbon dioxide... read more Sleep Apnea , should ask their doctor before using any benzodiazepines or sedatives (including over-the-counter sleep aids) or muscle-relaxing drugs because these drugs can worsen that disorder.

Botulinum toxin injected into the muscle or anesthetics injected into muscular trigger points have been used to relieve muscle spasms and pain.

In some cases of chronic pain, antidepressant drugs may be useful.

Regardless of the type of treatment, most people experience significant relief within about 3 months. If the symptoms are not severe, many people recover without treatment.

Internal temporomandibular joint derangement

In internal joint derangement with or without reduction, treatment is needed only if a person has jaw pain or trouble moving the jaw. People are often given NSAIDs for pain. If a person seeks treatment right after symptoms develop, a dentist or doctor may be able to manually move the disk back into its normal position.

If a person has had the disorder for fewer than 3 to 6 months, an oral anterior repositioning appliance may be used. The appliance holds the lower jaw forward, keeps the disk in position, and permits the supporting ligaments to tighten and become pain free. Over 2 to 4 months, the oral appliance is adjusted to allow the jaw to return back to its normal position, with the expectation that the disk will remain in place. However, the longer the disk is displaced, the less likely its repositioning will succeed.

A person with internal joint derangement with or without reduction should avoid opening the mouth wide—for instance, when yawning or biting into a thick sandwich—because injured joints are not as protected in these activities as they would be in a normal jaw. People with this disorder are advised to cut food into small pieces and to eat food that is easy to chew.

Sometimes the slipped disk becomes stuck in front of the temporomandibular joint (TMJ), preventing the jaw from opening fully. The disk must then be manually moved even further out of position to allow the joint to move fully. Passive jaw-motion devices, which stretch the jaw, have been used to slowly increase jaw motion. These devices are used several times a day. One such device is a threaded screw-type instrument that is placed between the front teeth and turned, much like a car jack, to gradually and gently push the disk forward, thereby creating a wider mouth opening. If such a device is not available, then a doctor may use a stack of tongue depressors placed between the front teeth, with an additional tongue depressor being added to the middle of the stack to increase mouth opening little by little.

If internal joint derangement cannot be treated by nonsurgical means, an oral and maxillofacial surgeon may need to do surgical procedures. However, the need for traditional surgery is rare since the introduction of procedures such as arthroscopy Arthroscopy A doctor can often diagnose a musculoskeletal disorder based on the history and the results of a physical examination. Laboratory tests, imaging tests, or other diagnostic procedures are sometimes... read more Arthroscopy . All surgical procedures are used in combination with oral appliance therapy, self-help measures, and supervision by a dentist or doctor.

Arthritis

A person with osteoarthritis in a temporomandibular joint needs to rest the jaw as much as possible, use an oral appliance or other device to control muscle tightness, and take an analgesic (such as acetaminophen or an NSAID) for pain. The pain usually goes away in 6 months with or without treatment. Even without treatment, most of the symptoms subside, probably because the band of tissue behind the disk becomes scarred and functions like the original disk. Usually, jaw movement is sufficient for normal activities, though the jaw may not open as wide as it used to. The oral appliance is usually worn while asleep, but it is sometimes also worn while awake.

Rheumatoid arthritis of the temporomandibular joint is treated with the medications used for rheumatoid arthritis Medications for Rheumatoid Arthritis Rheumatoid arthritis is an inflammatory arthritis in which joints, usually including those of the hands and feet, are inflamed, resulting in swelling, pain, and often destruction of joints.... read more Medications for Rheumatoid Arthritis of any joint. NSAIDs may be given for severe pain. Maintaining joint mobility and preventing fusion of the joint are particularly important. Usually, the best way to accomplish these goals is by exercising the jaw under a physical therapist's direction. To relieve symptoms, particularly muscle tightness, the person wears an oral appliance during sleep. If joint fusion prevents all movement of the jaw, the person may need surgery and, in rare cases, an artificial joint to restore jaw mobility.

Infectious arthritis is treated with antibiotics, proper hydration, pain control, and restriction of movement. Penicillin is usually the antibiotic used initially, until test results determine the type of bacteria present and thus the best antibiotic to use. Pus in the joint, if present, may be removed with a needle. Once the infection is controlled, people do jaw-opening exercises to help prevent scarring and limitation of motion.

Traumatic arthritis is treated with NSAIDs and corticosteroids (drugs that reduce inflammation and ease its symptoms such as swelling, redness, and pain), application of heat, a soft diet, and restriction of jaw movement.

Ankylosis

Occasionally, jaw-opening exercises can help, but people with bone fusion usually need surgery to restore jaw movement, and exercises are then needed for months to years to maintain the surgical correction.

Hypermobility

Prevention and treatment of dislocation resulting from hypermobility are the same as those for other causes of a dislocated jaw Jaw Dislocation A dislocated jaw (dislocated mandible) generally is a very painful, urgent dental problem that needs the prompt attention of a doctor or dentist. The mouth cannot be closed, and the jaw may... read more . When dislocation occurs, help is sometimes needed to snap the jaw back into position. Many people who experience repeated dislocations, however, learn how to maneuver the joint back into place themselves by consciously relaxing the muscles and lightly shifting the lower jaw until it pops back into place. To prevent recurrent dislocations, doctors may inject a substance into the joint (for example, blood) that causes scarring and thereby reduces mobility. Surgery to reshape the bone or tighten the ligaments around the temporomandibular joint is sometimes necessary to prevent recurrent dislocations.

Drugs Mentioned In This Article

Generic Name Select Brand Names
Amrix, Fexmid, Flexeril
7T Gummy ES, Acephen, Aceta, Actamin, Adult Pain Relief, Anacin Aspirin Free, Aphen, Apra, Children's Acetaminophen, Children's Pain & Fever , Children's Pain Relief, Comtrex Sore Throat Relief, ED-APAP, ElixSure Fever/Pain, Feverall, Genapap, Genebs, Goody's Back & Body Pain, Infantaire, Infants' Acetaminophen, LIQUID PAIN RELIEF, Little Fevers, Little Remedies Infant Fever + Pain Reliever, Mapap, Mapap Arthritis Pain, Mapap Infants, Mapap Junior, M-PAP, Nortemp, Ofirmev, Pain & Fever , Pain and Fever , PAIN RELIEF , PAIN RELIEF Extra Strength, Panadol, PediaCare Children's Fever Reducer/Pain Reliever, PediaCare Children's Smooth Metls Fever Reducer/Pain Reliever, PediaCare Infant's Fever Reducer/Pain Reliever, Pediaphen, PHARBETOL, Plus PHARMA, Q-Pap, Q-Pap Extra Strength, Silapap, Triaminic Fever Reducer and Pain Reliever, Triaminic Infant Fever Reducer and Pain Reliever, Tylenol, Tylenol 8 Hour, Tylenol 8 Hour Arthritis Pain, Tylenol 8 Hour Muscle Aches & Pain, Tylenol Arthritis Pain, Tylenol Children's, Tylenol Children's Pain+Fever, Tylenol CrushableTablet, Tylenol Extra Strength, Tylenol Infants', Tylenol Infants Pain + Fever, Tylenol Junior Strength, Tylenol Pain + Fever, Tylenol Regular Strength, Tylenol Sore Throat, XS No Aspirin, XS Pain Reliever
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