Products1 Aggrastat® (tirofiban hydrochloride) • In combination with heparin for treatment of acute coronary syndrome Arcoxia® (etoricoxib)2 • Osteoarthritis • Rheumatoid arthritis (in adults) • Acute pain • Chronic pain • Dysmenorrhea (menstrual pain) • Acute gouty arthritis Cancidas® (caspofungin acetate) • Treatment of invasive aspergillosis in patients who did not respond to or were intolerant of other antifungal therapies • Candida infections: intra-abdominal abscesses, peritonitis (infections within the lining of the abdominal cavity), pleural space infections (infections within the lining of the lung) • Candidemia (bloodstream infection) • Esophageal candidiasis Comvax® (Haemophilus b conjugate and hepatitis B [recombinant] vaccine) • Haemophilus influenzae type b disease and hepatitis B disease Cosopt® (dorzolamide hydrochloride and timolol maleate) • Lower intraocular pressure Cozaar® (losartan potassium) • High blood pressure • Reduction in progression of renal disease in patients with Type 2 diabetes and high blood pressure Crixivan® (indinavir sulfate) • HIV infection Fosamax® (alendronate sodium) • Treatment and prevention of postmenopausal osteoporosis • Reduction of osteoporotic fracture risk in postmenopausal women • Treatment of male osteoporosis to increase bone mass • Treatment of glucocorticoid-induced osteoporosis • Paget’s disease of the bone Hyzaar® (losartan potassium and hydrochlorothiazide) • High blood pressure Invanz® (ertapenem sodium) • Treatment of many aerobic and anaerobic bacteria, particularly community acquired, such as complicated intra-abdominal and complicated skin and skin structure infections Maxalt® (rizatriptan benzoate) • Acute migraine Pepcid AC® (famotidine)3 • Heartburn Propecia® (finasteride) • Treatment of male pattern hair loss Proscar® (finasteride) • Treatment of symptomatic benign prostate enlargement Singulair® (montelukast sodium) • Chronic asthma–adults and in children as young as age 2 • Seasonal allergic rhinitis–adults and in children as young as age 2 Stocrin® (efavirenz)4 • HIV infection Timoptic-XE® (timolol maleate ophthalmic gel forming solution) • Lower intraocular pressure Trusopt® (dorzolamide hydrochloride) • Lower intraocular pressure Vaqta® (inactivated hepatitis A vaccine) • Hepatitis A Varivax® (varicella virus vaccine live [Oka/Merck strain]) • Chickenpox Vioxx® (rofecoxib) • Osteoarthritis • Acute pain (in adults) • Rheumatoid arthritis (in adults) • Dysmenorrhea (menstrual pain) Zetia™ (ezetimibe)5 • Elevated total and LDL cholesterol levels Zocor® (simvastatin) • Elevated total cholesterol levels • Associated total/coronary mortality6 • Lower LDL cholesterol • Raise HDL cholesterol • Reduce triglycerides • Reduce stroke risk6 1This list excludes a number of older Company products introduced before 1990. 2Merck plans to refile an expanded New Drug Application (NDA) for Arcoxia to the U.S. Food and Drug Administration in the second half of 2003. 3Marketed by Johnson & Johnson • Merck Consumer Pharmaceuticals Co. 4Efavirenz is marketed by Bristol-Myers Squibb as Sustiva in the U.S., Canada and certain European countries, and by Merck in the rest of the world as Stocrin. 5Ezetimibe is under development around the globe (except in Japan) through a joint venture between Merck and Schering-Plough Corporation. 6In patients with coronary heart disease and elevated cholesterol.